placental barrier

In the range of safe dose , the permeability of bFGF through placental barrier was increased obviously .

在安全剂量范围（5～500ng/g）内，外源bFGF剂量增加到一定值（150ng/g）时，胎盘屏障通透性明显提高。

Conclusions BFGF can penetrate placental barrier , and protect brain cells from hypoxia and stimulate neurons proliferation .

结论bFGF能够通过胎盘屏障并促进宫内窘迫胎鼠神经元增殖并增加神经元存活数。

Observation on the level of propylthiouracil crossing the placental barrier

丙基硫氧嘧啶通过胎盘程度的观察

It was suggested that swainsonine could damage placenta and endanger directly fetuses through placental barrier .

由此证明，苦马豆素能损害胎盘并通过胎盘屏障直接作用胎儿。

Placental barrier breakage in preeclampsia : Ultrastructural evidence

先兆子痫胎盘屏障破损：超微结构证据

Study on permeability of brain derived neurotrophic factor through placental barrier and fetal blood brain barrier after transient uteroplacental ischemia

脑源性神经营养因子在宫内缺氧环境中对胎盘及血脑屏障通透性的实验研究

Some environmental pollutants can transplacentally transfer from mothers to their fetuses for the limited function of placental barrier .

由于胎盘屏障功能有限，母体内的一些环境污染物进入胎儿体内。

Trophoblast cells , as the outermost covering of placental barrier , are directly bathed in the maternal blood .

胎盘滋养层细胞作为胎盘屏障的第一层细胞，直接与母亲血液接触，以往的组织病理学研究也已经得到滋养层细胞感染的证据，但其确切机理国内尚未见报道。

The results showed that in different periods urethan could penetrate through the placental barrier to effect the normal enzyme patterns of the developing liver significantly .

结果发现在不同妊娠时期，这种化合物对胚胎及生后仔鼠肝脏酶活性均有明显影响。

Objective To investigate the proof of fetal cells passing through the placental barrier into the maternal peripheral blood to provide laboratory data for the non invasive prenatal gene diagnosis of genetic diseases .

目的从胎盘组织中寻找胎儿细胞穿越胎盘屏障，进入孕妇外周血的实验室证据，为利用孕妇外周血进行无创性产前基因诊断提供实验依据。

Conclusion MCLR passes through the placental barrier and causes damage in kidney and liver , which may be the basis of high incidence of liver caner in the fetus phase .

结论MCLR可透过胎盘屏障造成肝、肾等脏器损伤，可能在胚胎期就已形成肝癌高发基础。

The direct serum infection method is used to simulate the natural HBV infection of trophoblastic cells or HUVEC separately , and then the possibility of HBV infection of human placental barrier is discussed .

采用血清直接感染法进行滋养层细胞的HBV感染，模拟自然状态下HBV分别感染胎盘屏障中的滋养层细胞及内皮细胞，然后感染构建的胎盘体外屏障，探讨HBV感染胎盘屏障的可能性。

Low-dose cadmium can penetrate the placental barrier of the rats and distribute to the brain , heart , liver , kidneys and other organs of the foetuses .

低剂量镉可以通过大鼠胎盘屏障并分布到胎鼠体内的脑、心脏、肝脏和肾脏等多个脏器。

Conclusion Excessive fluoride can directly through the placental barrier , influence cell structure and cell cycle distribution of fluorosis rat offspring and render the cell cycle stagnant in S phase , induce apoptosis .

结论过多的氟化物可以通过胎盘屏障直接作用于仔鼠颅骨成骨细胞，引起成骨细胞结构、细胞周期的改变，并可致细胞凋亡。

Permeability of Exogenetic BDNF Through Placental Barrier and Blood-brain Barrier in Rats with Transient Uteroplacental Ischemia and Its Effection on Apoptosis of Embryo Brain and Its Signal Pathways

外源性BDNF在宫内缺氧环境中对胎盘及胚鼠血脑屏障通透性和脑细胞凋亡的作用及信号传导的研究

Trophoblast cells , as the outermost covering of placental barrier , are bathed in maternal blood and contact with viral particle directly , might be the key location for virus invasion into placental .

滋养层细胞为屏障的最外层，直接浸浴于母血中，可能与母体的病毒颗粒直接接触而成为病毒侵入胎盘的关键部位。

( 3 ) Automobile exhaust has genetic toxicity . It can get across the placental barrier and interfere with cell division . It can also trigger the chromosomal aberration and breakage and cause the damage of DNA .

汽车尾气具有遗传毒性，可通过胎盘屏障，干扰细胞分裂，诱发染色体畸变、断裂及引起DNA的损伤。

Pregnancy : Coumadin is contraindicated in women who are or may become pregnat because the drug basses through the placental barrier and may cause fatal hemorrhage to the felus in utero .

妊娠期禁用：香豆定禁用于孕妇，或可能已怀孕的妇女，因为本品可能穿过胎盘屏障，引起子宫内胚胎致命的出血。

Conclusion ( 1 ) The main route of HBV transmission from mother to fetus is transplacental , the transplacental transmission of HBV may be a cellular transfer , Placental barrier can offer conservancy effect on fetus to some extent .

结论新生儿宫内感染与孕妇乙肝感染状态有关，HBV宫内感染以经胎盘感染为主，感染胎儿的途径可能是通过细胞转移方式实现的，胎盘屏障对胎儿有一定的保护作用。

A woman is at risk of giving birth to a child with fetal alcohol syndrome if she drinks while pregnant.Fetal alcohol syndrome ( FAS ) is a condition that affects the developing fetus when alcohol passes through the placental barrier .

如果怀孕了还喝酒，那这就是把自己的孩子置于患上胎儿酒精综合症的危险之中。胎儿酒精综合症，是酒精透过胎盘屏障影响生长中的胎儿的一种情况。

Objective To study the distribution of selected nutritional and toxic trace elements in mother 's hair , venous blood , and cord blood , and the blocking effects of the placental barrier to the transportation of trace elements from mother to her baby .

目的研究必需和非必需微量元素在正常产妇毛发、静脉血及胎儿脐血间的分布规律，探讨胎盘屏障对母体和胎儿间微量元素转运的影响。

The glycerin fructose as an effective free radical scavenger . It had good stability in human , it can penetrate the placental barrier and protect the neonates ' brain through improving the blood circulation . Its mechanism might be related to ameliorate the oxidative injuries . 2 .

结论：1、甘油果糖是一种有效的自由基清除剂，在人体内有良好的稳定性，可通过人体胎盘屏障对宫内窘迫胎儿有保护作用，其机制与减轻脂质过氧化损伤有关。

Previous studies suggested that , a variety of adverse intrauterine environments ( e.g. maternal stress ) could decrease placental 11 β - HSD-2 expression and thus open the placental barrier . Finally , the fetus was overexposed to maternal GC .

研究提示，多种不良宫内环境（如孕妇应激）可降低胎盘11p-HSD-2的表达而开放胎盘屏障，使胎儿过暴露于母源性GC。

Conclusions : Prenatal caffeine exposure could cause maternal stress and / or increase the placental 11 β - HSD-1 / 11 β - HSD-2 expression ratio , impair the placental barrier to maternal GC and finally cause the over exposure of maternal GC to fetus .

结论：孕期咖啡因暴露能通过母体应激和/或增加胎盘11β-HSD-1/11β-HSD-2的表达比，削弱胎盘对母源性GC的屏障作用，引起胎儿母源性GC过暴露。

Objective To explore the methods of culture and identification of human placental microvascular endothelial cells ( HPMVEC ) in vitro , aiming to construct the polar model of human placental barrier .

目的探索人胎盘微血管内皮细胞的体外培养方法，并对其进行鉴定，为构建体外人胎盘屏障极性模型奠定基础。